Vitamin B12 has several important functions including making red blood cells and releasing energy from the food you eat. Cobalt is a major part of the structure of vitamin B Therefore, if you get enough vitamin B12, you will also get enough cobalt.
Having too much cobalt could be harmful. However, cobalt is currently not used in supplements in the UK and the amount we get from food is not harmful. Having high amounts of cobalt for long periods of time could affect the heart and might decrease fertility in men. We will not reply to your feedback.
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Contacts for common benefits are listed below. Call Email dcs. Vitamin B12 is also notable for its cobalt—carbon bond, making it the only known naturally occurring organometallic complex. Similarly, many new developments in cobalt chemistry focus on organometallic compounds. In the field of catalysis, for example, cobalt has been found to mediate many of the cross-coupling reactions dominated for years by palladium and nickel. Furthermore, cobalt-based catalysts are also amongst the many systems being looked at for mediating the so-called oxygen evolution reaction OER — a fundamental step in the photochemically driven splitting of water into hydrogen and oxygen.
The development of efficient technologies based on this process could ultimately lead to environmentally benign energy sources that harness the power of the Sun.
Historically, the most important application of organocobalt complexes in catalysis has been in the transformation of alkenes into aldehydes through a process known as hydroformylation. The classical catalyst for this reaction is the protonated derivative of the tetracarbonylcobaltate anion — HCo CO 4. Although more selective catalysts, often rhodium-based, have been developed over the years, the cobalt system is still used for many applications.
Being a group 9 element, cobalt does not form a neutral monometallic carbonyl complex. Instead, it forms a dimer — dicobalt octacarbonyl — with a bent cobalt—cobalt bond. This dinuclear compound is also used as a hydroformylation catalyst, but another important reaction is one in which it reacts with alkynes — with loss of two molecules of carbon monoxide — to give alkyne—hexacarbonyl—dicobalt complexes.
These air-stable and deep-red compounds can catalyse the cyclotrimerization of alkynes to make substituted benzenes, but their main preparative use is in the formation of substituted cyclopentenones. The use of alkyne—cobalt complexes in such synthetically efficient and direct ring-forming processes was serendipitously discovered at the University of Strathclyde, Scotland, in Following on from his pioneering work on the synthesis and reactivity of ferrocene, Peter L.
Pauson turned his attention to the fundamental aspects of cobalt-mediated alkyne trimerization. Believing that sufficiently reactive alkenes may be able to react with alkyne—cobalt complexes in a similar fashion to alkynes, the appreciably strained alkene norbornene was investigated.
The main organic products isolated from the reactions were cyclopentenones, formed from the combination of one unit each of the alkyne, alkene and carbon monoxide. This accidental, yet extremely fortunate, discovery led to vigorous research efforts in the Strathclyde laboratories over subsequent years in an effort to establish the scope and limitations of this process for the one-pot formation of selectively substituted cyclopentenones.
Indeed, such is the importance of substituted five-membered-ring ketones in organic chemistry, that many related metal-mediated processes for constructing such small ring systems have now evolved from these initial discoveries, and remain the focus of intense international research effort.
To almost all organic chemists the world over, this now renowned type of ring-building process is known as the Pauson—Khand reaction — that is, with the exception of one chemist: Pauson himself. This vitamin is essential for making red blood cells erythropoiesis. It also maintains the nervous system. Cobalt has some of the same jobs as manganese and zinc. It can replace manganese in activating several enzymes. These are called biochemical reaction activators.
It can also replace zinc in some biochemical reactions. Cobalt is also part of the biotin-dependent Krebs cycle. This is the process that the body uses to break down sugars into energy. As part of B, cobalt is used to prevent pernicious anemia. As part of supplements, cobalt is measured in micrograms mcg. The average adult intake of cobalt is 5 to 8 mcg per day.
Trace amounts of cobalt are found in most foods. Foods high in vitamin B are the only source of cobalt used by the body.
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