Such loci are termed VNTRs. The total number of base pairs at this locus could vary from to In this diagram, only three different variants alleles are illustrated for the VNTR locus, but 50 or more different alleles are often found at human VNTR loci.
Analysis of a VNTR locus by Southern hybridization most commonly results in a two-band pattern, comprised of a band inherited from each parent. A one-band pattern can occur if the size of the two parental bands are the same or nearly the same.
For our simple example of three different alleles designated A, B, and C illustrated above, six unique DNA profiles are possible. References Anchordoquy, H. Genotyping of three candidate genes after whole-genome preamplification of DNA collected from buccal cells.
Behavior genetics, 33 1 , Blackburn, G. Short tandem repeat typing technologies used in human identity testing. Biotechniques, 43 4 , Sii-Sv. Butler, J. Biological identification systems: genetic markers. Hammond, H. In utero paternity testing following alleged sexual assault: a comparison of DNA-based methods.
JAMA, 22 , Hamzah, K. Molecular prevalence of Anaplasma phagocytophilum in sheep from Iraq. Open Veterinary Journal, 9 3 , — Kim, J. Development and forensic validation of human genomic DNA quantification kit.
International journal of legal medicine, Lee, H. Differential distribution of human mitochondrial DNA in somatic tissues and hairs. Annals of human genetics, 70 1 , Musimba, N. Current Research in Agricultural Sciences, 2 2 , Sequence heterogeneities of genes encoding 16S rRNAs in Paenibacillus polymyxa detected by temperature gradient gel electrophoresis.
Journal of bacteriology, 19 , Parker, P. What molecules can tell us about populations: choosing andusing a molecular marker. Ecology, 79 2 , Pray, L. Nature Education, 1 1 , Ramazanzadeh, R.
Variable number of tandem repeats VNTR and its application in bacterial epidemiology.
0コメント